LUNG METASTASIS AT INITIAL PRESENTATION IN A 3 YEAR OLD GIRL WITH STAGE IV WILMS TUMOR

Lung metastasis at initial presentation in a 3 year old girl with stage IV Wilms tumor

Lung metastasis at initial presentation in a 3 year old girl with stage IV Wilms tumor

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Background: Wilms tumor (nephroblastoma) is a malignant pediatric moen finney tumor that arises from mesodermal embryological precursors of renal parenchyma.Lung metastasis as the first presentation of nephroblastoma occurs in 20% of cases.However, haematogenous spread to the lungs or to regional lymphnodes from a previously diagnosed nephroblastoma occurs in of 85% of cases.Case report: A 3-year old girl presented at children emergency unit with cough and weight loss.Examination revealed an emaciated child, with a huge, right sided abdominal mass.

Abdominal ultrasound scan showed a heterogenous, spherical mass with irregular anechoic areas and echogenic solid areas in kidney.Chest radiograph revealed bilateral cannon ball opacities.A diagnosis of nephroblastoma with lung metastasis was made.She underwent combined therapy but relapsed one yale law school colors year later.

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